Cervix - Cytology
Normal cells / nonneoplastic findings
Endometrial cells

Author: Xinmsn Zhang, M.D. (see Authors page)

Revised: 1 May 2017, last major update August 2010

Copyright: (c) 2006-2017, PathologyOutlines.com, Inc.

PubMed search: cervix endometrial cells [title]

Cite this page: Cytology - Endometrial cells. PathologyOutlines.com website. http://pathologyoutlines.com/topic/cervixcytologyendometrialcells.html. Accessed May 22nd, 2017.
Definition / general
  • Spontaneously exfoliated endometrial cells are often seen during the first 12 days of the menstrual cycle
  • May also be due to hormone replacement therapy (Obstet Gynecol 2002;100:445) or tamoxifen
  • Endocervical sampling devices may inadvertently sample the lower uterine segment or endometrium
Clinical features
Cytology description
  • Exfoliated endometrial cells often present as small cells arranged in balls with scant cytoplasm, dark nuclei and nuclear molding and fragmentation
  • Abraded endometrial cells may present as large and small tissue fragments with glands and stromal cells
  • Resemble histiocytes
  • Easier to identify if in clusters
Cytology images

Images hosted on PathOut server:

Thin Prep of normal endometrial
group - postmenstrual cycle,
contributed by Dr. Carmen Luz, Spain



Images hosted on other servers:

IUD related changes

Contributed by Dr. Marilin Rosa
University of Florida (USA)