Cervix
Benign / nonneoplastic lesions
Blue nevus

Author: Branko Perunovic, M.D. (see Authors page)

Revised: 14 April 2017, last major update May 2007

Copyright: (c) 2007-2017, PathologyOutlines.com, Inc.

PubMed Search: Blue nevus cervix

Cite this page: Blue nevus. PathologyOutlines.com website. http://pathologyoutlines.com/topic/cervixbluenevus.html. Accessed April 24th, 2017.
Definition / General
  • Present in up to 2% of cervices; may be more common in Japanese women, particularly if step sections are obtained (Acta Pathol Jpn 1991;41:751)
  • 20% are multiple
  • Usually an incidental finding
Case Reports
Gross Description
  • Blue / black, flat up to 3 cm
  • Usually ill defined in lower endocervix
Micro Description
  • Elongated, wavy dendritic cells in clusters or individually, below endocervical epithelium
  • Cytoplasm has brown melanin
  • Stromal macrophages
Micro Images

Images hosted on PathOut server:

Pigment containing nevus cells in cervical stroma

Positive Stains
Negative Stains
Electron Microscopy Description
Differential Diagnosis
  • Hemosiderin: coarse granules are refractile and iron+, Fontana-Masson negative; pigment is in macrophages, not spindle cells
  • Melanoma: junctional change, stromal infiltration by malignant cells
  • Melanosis: basal epithelium only, not in stroma
Additional References