Cite this page: CD234. PathologyOutlines.com website. http://pathologyoutlines.com/topic/cdmarkerscd234.html. Accessed May 25th, 2017.
Definition / general
- Aka Duffy blood group antigen (Fy glycoprotein); erythrocyte chemokine receptor, Duffy Antigen Receptor for Chemokines (DARC)
- RBC receptor for Plasmodium vivax, a malarial parasite
- Negativity associated with sickle cell trait, due to common protection against malaria provided by both traits African-Americans often Duffy negative and resistant to P. vivax malaria
Positive staining - normal
- Endothelial cells of post-capillary venules, Purkinje cells of cerebellum