Table of ContentsDefinition / general
Cite this page: CD221. PathologyOutlines.com website. http://pathologyoutlines.com/topic/cdmarkerscd221.html. Accessed January 20th, 2018.
Definition / general
- Aka insulin-like growth factor 1 receptor
- Mediates insulin stimulated DNA synthesis and IGF1 stimulated cell proliferation and differentiation
- Often overexpressed in malignant tissue, where it functions as an anti-apoptotic agent by enhancing cell survival