Cite this page: CD207. PathologyOutlines.com website. http://pathologyoutlines.com/topic/cdmarkerscd207.html. Accessed November 22nd, 2017.
Definition / general
- Aka langerin (Langerhans cell specific c-type lectin)
- Functions as endocytic receptor
- Localized to Birbeck granules
- Mannose binding to this protein may cause antigen internalization into Birbeck granules and access to a nonclassical antigen-processing pathway
Positive staining - normal
- Langerhans cells (immature dendritic cells of epidermis and mucosa)