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CD Markers
CD10

Reviewer: Nat Pernick, M.D. (see Reviewers page)
Revised: 2 September 2013, last major update September 2013
Copyright: (c) 2002-2013, PathologyOutlines.com, Inc.
PubMed Search: CD10[title]

General
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Terminology
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Pathophysiology
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Uses by pathologists
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Acute lymphoblastic leukemia (ALL): Bladder: Breast: Ectopic prostate: Endometrial stromal tumors: Endometriosis: Gynecologic tumors: Hepatocellular carcinoma vs. non-hepatocellular carcinoma: Kidney Lymphoma: angioimmunoblastic T cell (AITL): Lymphoma: Burkitt: Lymphoma: diffuse large B cell: Lymphoma: follicular: Microvillous inclusion disease: Pancreas: Skin tumors: Vascular tumors:

Micro images
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Quality control


Bladder:

Noninvasive and invasive urothelial carcinoma

Bladder urothelial carcinoma


Breast:

Myoepithelium (fig B, F)

Adenosis (fig B)

Normal and DCIS

DCIS

Stromal staining in invasive ductal carcinoma

Invasive ductal carcinoma


Malignant phyllodes tumor


CNS:

Hemangioblastoma (CD10-) vs. metastatic renal cell carcinoma (CD10+)


Kidney:

Kidney hemangioblastoma (fig D)



Leukemia / lymphoma:

Diffuse large B cell lymphoma


Pre-T ALL

Reactive T cells may be CD10+


Liver: hepatocellular carcinoma:

Canalicular pattern in hepatocellular carcinoma (figure B)


Lung:

COPD


Lymph node:

Metastatic prostate carcinoma

Metastatic seminoma



Pleura:

Epithelioid hemangioendothelioma



Skin:

Basal cell carcinoma (fig B)

Basal cell carcinoma (fig B)

Melanoma


Squamous cell carcinoma (fig B)

Trichoepithelioma

Trichoepithelioma



Small intestine:

Normal enteric brush border

Microvillous inclusion disease

Enterocolic anastomosis


Crohn ileitis

Chronic, treatment-
refractory pouchitis

Backwash ileitis



Uterus: benign

Endometriosis

CD10- stromal cells

Leiomyoma, cellular


Uterus: endometrial stromal sarcoma:

Extrauterine (fig 4, inset ER)

Myxoid-fibrous (fig 4)

Various images


Uterus: endometrial adenocarcinoma:

Invasive

With adenomyosis


Malignant mixed mullerian tumor


Positive staining - normal
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Positive staining - disease
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Negative staining
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Flow cytometry images
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CD10+ vs. CD10- diffuse large B cell lymphoma

End of CD Markers > CD10


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