Breast malignant, males, children
Carcinoma subtypes
Tall cell like tumors

Author: Monika Roychowdhury, M.D. (see Authors page)

Revised: 30 December 2016, last major update August 2012

Copyright: (c) 2001-2016,, Inc.

PubMed Search: tall cell variant of papillary thyroid carcinoma
Cite this page: Tall cell like tumors. website. Accessed April 26th, 2017.
Definition / General
  • Not part of WHO breast classification
Clinical Features
Micro Description
  • Solid or papillary nests of columnar / cuboidal cells with eosinophilic granular cytoplasm, round / oval nuclei with sharply defined nuclear membrane, nuclear grooves and eosinophilic pseudoinclusions
  • Also psammoma bodies
Cytology Description
  • Abundant cellularity with isolated cells, sheets and papillary formations of epithelial cells with nuclear grooves (Int J Surg Pathol 2006;14:79)
Positive Stains
Negative Stains
Electron Microscopy Description
  • Cytoplasmic granules are mitochondria
Molecular / Cytogenetics Description
  • No BRAF mutations of thyroid carcinoma
Differential Diagnosis
  • Metastatic tall cell variant of papillary thyroid carcinoma: clinical history of thyroid disease, thyroglobulin+, TTF1+ (Ann Pathol 1998;18:130)