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General
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Terminology
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Epidemiology
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Clinical features
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Prognostic features
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Case reports
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Treatment
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Clinical images
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Mammogram, courtesy of Dr. Mark R. Wick

Gross description
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Gross images
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Pure, courtesy of Dr. Mark R. Wick

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Gelatinous or jelly-like cut surface

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Ill-defined margins

Soft, gelatinous mass

AFIP

Tumor with positive margin (Fig 1A/1B)

Soft, gelatinous mass

Micro description
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Micro images
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Pure, courtesy of Dr. Mark R. Wick

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Mucicarmine stain, courtesy of Dr. Mark R. Wick

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Parenchyma, courtesy of Dr. Mark R. Wick

Case of the Week #11

Nuclear atypia is mild

Nuclear grading of intermediate

Abundant extracellular mucin

Abundant mucinous stroma containing epithelial tumor cells with at most mild atypia

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Cells in pools of extracellular mucin

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Mucin is extracellula

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Irregular nests and clusters of tumor cells

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Nuclei are plump and vesicular

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Anastomosing nests

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Well-differentiated tumor cells

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Cribriform pattern

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Small clusters of tumor cells

Contributed by: Dr. Semir Vranic, University of Sarajevo (Bosnia)



AFIP images:

Clusters of tumor cells in mucinous secretion suround a duct

Alveolar and festoon patterns surrounded

Sparse epithelial component (arrow-DCIS) by mucin

Clusters of tumor cells

Grimelius staining (an agryophilic silver stain) denotes neuroendocrine differentiation



ER+, PR+, chromogranin+and synaptophysin+

Tumor cells are ER+

H&E, CU-18

EMA

H&E



Cytology description
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Cytology images
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Grimelius stain, courtesy of Dr. Mark R. Wick

Papanicolaou

MGG

Various images

Colloid carcinoma

Videos
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Positive stains
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Negative stains
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Molecular description
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Electron microscopy description
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Electron microscopy images
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Cytoplasmic mucigen granules

Differential diagnosis
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End of Breast malignant, males, children > Carcinoma subtypes > Mucinous / colloid carcinoma



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