Breast malignant, males, children
Carcinoma subtypes
Metastases to breast

Author: Monika Roychowdhury, M.D. (see Authors page)

Revised: 29 December 2016, last major update October 2012

Copyright: (c) 2001-2016, PathologyOutlines.com, Inc.

PubMed search: carcinoma [title] "metastases" to breast

Cite this page: Metastases to breast. PathologyOutlines.com website. http://pathologyoutlines.com/topic/breastmalignantmet.html. Accessed March 29th, 2017.
Definition / General
Clinical Features
  • Rare (1% - 2% of breast tumors), usually from contralateral breast (Arch Pathol Lab Med 2008;132:931)
  • Also lung, melanoma, ovary, kidney, stomach and thyroid (World J Surg Oncol 2007;5:74)
  • Usually occurs in patients with advanced disease
  • In children, rhabdomyosarcoma (alveolar variant) is most common metastasis to breast
Case Reports
Gross Description
  • Often superficial (in soft tissue), well circumscribed firm nodules without skin retraction or peau d’orange
Gross Images
Images hosted on other servers:

Colonic adenocarcinoma

Micro Description
  • Most important feature is that it does not resemble a primary breast carcinoma
  • Usually no ductal carcinoma in situ (DCIS), although infiltrative pattern may resemble DCIS (Ann Diagn Pathol 2001;5:15)

Metastatic ovarian or peritoneal serous carcinoma to breast or axilla:
Micro Images
Images hosted on PathOut server:

Various images

Small intestinal carcinoid - chromogranin+



Images hosted on other servers:

Choriocarcinoma: antibody to hCG

Colonic adenocarcinoma

Lung: neuroendocrine carcinoma

Chromogranin+


Synaptophisin+

Renal cell carcinoma

Small intestinal carcinoid

Infiltrating nests of tumor within small intestinal wall

Cytology Images
Images hosted on other servers:

Left: medulloblastoma; right: melanoma

Negative Stains