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General
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Epidemiology
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Prognostic features
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Case reports
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Treatment
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Clinical images
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Mammogram, large cell, courtesy of Dr. Mark R. Wick

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Mammogram, lymphoblastic, courtesy of Dr. Mark R. Wick

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Large cell, courtesy of Dr. Mark R. Wick

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Large cell, breast skin, courtesy of Dr. Mark R. Wick

Gross description
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Gross images
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Large cell, parenchyma, courtesy of Dr. Mark R. Wick

Micro description
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Micro images of subtypes
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Anaplastic large cell lymphoma:

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Large cells with abundant cytoplasm

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Associated with silicon implant

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Various images

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Sarcomatoid variant



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ALK neg cases

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TIA+ and ALK+

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By Dr. Mark R. Wick: H&E, ALK1, CD30




Burkitt’s lymphoma:

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Various images

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PAX5 stain, courtesy of Dr. Mark R. Wick



CLL / SLL:

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Xray, H&E, CD5, CD20 - Contributed by Dr. Julia Braza, Beth Israel Deaconness Medical Center, Boston, Massachusetts




Diffuse large B cell lymphoma:

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Rapidly growing mass

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Large cells with 1 or more nucleoli

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Large centroblasts and starry sky macrophages

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H&E and CD20

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Weak BCL10+

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Various images

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Mixed with MALT

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Various images


Diffuse large B cell, courtesy of Dr. Mark R. Wick:

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Parenchyma

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Green pyronine



Follicular lymphoma:

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Bulging and fleshy tumor

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Follicular lymphoma

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Courtesy of Dr. Mark R. Wick

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BCL2+




Lymphoblastic lymphoma, courtesy of Dr. Mark R. Wick:

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CD10

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TDT




Mantle cell lymphoma:

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Various images




Marginal zone / MALT lymphoma:

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H&E, CD20, BCL10

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By Dr. Mark R. Wick




NK lymphoma, nasal type:

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Lobular pattern of infiltration

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Abundant cytoplasm and irregular nuclei

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Pan-keratin high lights lymphoepithelial lesions

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TIA+ and CD56+



Peripheral T cell lymphoma:

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CD4+ large cell tumor

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Clear cytoplasm and mitotic activity

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CD8+ tumor

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Abundant cytoplasm and atypia



Plasmablastic lymphoma:

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HIV+, by Dr. Mark R. Wick



Cytology images
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Large cell (Diff Quik)
By Dr. Mark R. Wick

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Discohesive cells - subtype not specified

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Lymphoblastic, parenchyma, courtesy of Dr. Mark R. Wick

Positive stains
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Negative stains
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Differential diagnosis
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Additional references
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End of Breast malignant, males, children > Other malignancies > Lymphoma



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