Breast – Malignant, Males, Children - Carcinoma with melanotic features

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Breast-malignant, males, children

Carcinoma with melanotic features

Author: Nat Pernick, M.D, PathologyOutlines.com, Inc.

Reviewer: Daniel Visscher, M.D., University of Michigan Hospitals, February 2009 (see Reviewers page)

Revised: 24 September 2009

Last major update: August 2009

Definition

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● Part of WHO classification,

● Combination of ductal carcinoma and melanoma

● Rare

Case reports

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● 38 year old woman (Pathol Int 2009;59:676)

● Ductal carcinoma with differentiation to melanoma (AJSP 1999;23:1280)

Micro Images

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Melanin pigment but NOT melanoma

Differential Diagnosis

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● Lipofuscin (Histopathology 2000;37:456) or melanin pigment (Ultrastruct Pathol 2000;24:109, Br J Dermatol 1998;139:287) in otherwise typical ductal carcinoma

● Metastatic melanoma

End of Breast – Malignant, Males, Children > Carcinoma with melanotic features

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