Breast - nonmalignant
Benign tumors / changes
Lymphangioma

Author: Nat Pernick, M.D. (see Authors page)

Revised: 8 August 2017, last major update April 2010

Copyright: (c) 2002-2017, PathologyOutlines.com, Inc.

PubMed Search: Lymphangioma [title] breast

Cite this page: Lymphangioma. PathologyOutlines.com website. http://pathologyoutlines.com/topic/breastlymphangioma.html. Accessed November 18th, 2017.
Definition / general
  • Either congenital or acquired
Terminology
  • Congenital lesions are also called cystic hygroma
  • Acquired lesions are also called lymphangiectasis
  • Lymphangioma circumscriptum: the classic lesion appears at birth or in early years but most cases described in literature are postsurgery or radiation therapy
  • See also Atypical or benign vascular lesion, postradiation
Epidemiology
  • 90% of congenital lesions present by age 2 years
Clinical features
  • Congenital lesions are very rare
  • Tends to infiltrate surrounding tissues
  • Associated with pain, chronic drainage, cellulitis (South Med J 1999;92:69)
Case reports
Treatment
Clinical images

Images hosted on PathOut server:

Superficial, breast skin, contributed by Dr. Mark R. Wick



Images hosted on other servers:

Vesicles on breast

Oozing of clear fluid from vesicles

  

Extensive sponge-like
subcutaneous tissue containing
serous fluid and lying between
the skin and the muscle layer

Microscopic (histologic) description
  • Dilated lymphatics involve superficial and deep dermis and possibly subcutaneous tissue, occasionally fascia and skeletal muscle
  • May have hemosiderin deposition
Microscopic (histologic) images

Images hosted on PathOut server:

Superficial, breast skin, contributed by Dr. Mark R. Wick



Images hosted on other servers:

Distended lymphatic channels interspersed with breast lobules; lymphatic channel has attenuated lining

Papillary dermis shows ectatic lymphatic spaces

Neck (not breast)


Contributed by: Dr. Semir Vranić, University of Sarajevo (Bosnia)

Electron microscopy description
  • Endothelial cells have cytoplasmic microfilaments and pinocytotic vesicles
  • Intermediate junctions are present between adjacent cells (Jpn J Clin Oncol 1991;21:129)
Differential diagnosis
Additional references