Breast - nonmalignant
Benign tumors / changes
Leiomyoma

Author: Hind Nassar, M.D. (see Authors page)

Revised: 8 August 2017, last major update April 2010

Copyright: (c) 2002-2017, PathologyOutlines.com, Inc.

PubMed Search: Leiomyoma [title] breast

Cite this page: Leiomyoma. PathologyOutlines.com website. http://pathologyoutlines.com/topic/breastleiomyoma.html. Accessed September 21st, 2017.
Definition / general
  • Benign smooth muscle tumor similar to counterparts elsewhere
Epidemiology
  • Rare in breast
Sites
  • Usually involves nipple
Etiology
Clinical features
Case reports
Treatment
  • Complete excision to prevent recurrence
Clinical images

Images hosted on PathOut server:

Breast skin, contributed by Dr. Mark R. Wick

Gross description
  • Often ill defined
Microscopic (histologic) description
  • Interlacing bundles of spindle cells with eosinophilic cytoplasm and blunt ended, cigar shaped nuclei
  • May have epithelioid or granular features
  • No atypia, no hypercellularity, no / rare mitotic figures ( < 3 per 10 HPF), no necrosis
Microscopic (histologic) images

Images hosted on PathOut server:

Breast skin, contributed by Dr. Mark R. Wick

Circumscribed tumor of spindled cells without atypia



Images hosted on other servers:

Spindled cells with rounded ends

Negative stains
Differential diagnosis