Breast
Cytopathology Competency Assessment
Benign Breast Neoplasms

Author: Gordon H. Yu, M.D. (see Authors page)

Revised: 2 June 2016, last major update September 2012

Copyright: (c) 2012-2016, PathologyOutlines.com, Inc.

Cite this page: Cytology/Competency Assessment - Benign Breast Neoplasms. PathologyOutlines.com website. http://pathologyoutlines.com/topic/breastcytcompneoplasms.html. Accessed April 25th, 2017.
Medical Knowledge
  1. Benign Breast Adenomas
    1. Ductal Adenoma
      1. Become familiar with the cytomorphologic features of this unusual benign tumor of older women
    2. Tubular Adenoma
      1. Become familiar with the cytomorphologic features of this lesion, including features useful in its distinction from tubular carcinoma
    3. Adenosis Tumor
    4. Microglandular Adenosis
    5. Radial Scar/Complex Sclerosing Lesion
    6. Nipple Adenoma
      1. Recognize the cytomorphologic features of this lesion, including hypercellularity, and its differential diagnosis
  2. Fibroepithelial Tumors
    1. Fibroadenoma
      1. Recognize the clinical presentation of this common benign neoplasm
      2. Recognize that these lesions contain both stromal and epithelial components
      3. Become familiar with the cytomorphologic features of this lesion, recognizing that the differential diagnosis includes fibrocystic disease (with epithelial hyperplasia) and that definitive distinction of these lesions may not be possible by FNA alone
      4. Become aware of the possibility of false-positive diagnoses due to the hypercellularity and focal cytologic atypia often observed in aspirates of fibroadenoma
      5. Recognize benign features in FNA smears of fibroadenoma which, when noted, allow the avoidance of a false-positive diagnosis of malignancy
    2. Phyllodes tumors
      1. Learn the typical presentation of this tumor and its relatively rare occurrence
      2. Learn the typical clinical course of this tumor
      3. Understand the histologic appearance of this lesion and its histologic distinction from fibroadenoma
      4. Become familiar with the cytomorphologic features of phyllodes tumor, particularly the presence of large, cellular stromal fragments
      5. Appreciate the limitations of FNA biopsy in the diagnosis of this lesion and that separation of phyllodes tumor from fibroadenoma may not always be possible on the basis of FNA alone
Systems Based Practice
  1. Recognize the values of clinical history, physical examination findings and radiologic studies when interpreting FNAs of fibroepithelial lesions which may favor the diagnosis of fibroadenoma or phyllodes tumor