Anus & perianal area
General
Grossing & features to report
Author: Nat Pernick, M.D.
Last author update: 1 April 2005
Last staff update: 3 December 2021
Copyright: 2002-2024, PathologyOutlines.com, Inc.
PubMed Search: Anus features to report for tumors
Table of Contents
Grossing (pending) | Features to report - General | Features to report - Polypectomy (excisional biopsy) - applies to all invasive carcinomas | Features to report - Local excision (transanal disk excision) - applies to all invasive carcinomas | Features to report - Anus resection - applies to all invasive carcinomasCite this page: Pernick N. Grossing & features to report. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/anusreport.html. Accessed April 26th, 2024.
Grossing (pending)
Features to report - General
- Mandatory / optional are for accreditation purposes by the American College of Surgeons Committee on Cancer
- Features to report by organization:
Features to report - Polypectomy (excisional biopsy) - applies to all invasive carcinomas
- Mandatory
- Polyp size: at least 1 dimension
- Histologic type: squamous cell carcinoma, adenocarcinoma, mucinous adenocarcinoma, small cell carcinoma, undifferentiated carcinoma, other, carcinoma - cannot determine
- Histologic grade: well, moderate or poorly differentiated, undifferentiated, cannot determine or not applicable; for adenocarcinoma, is based on percentage of tumor that forms glands: well: > 95%, moderate: 50 - 95%, poor: 5 - 49%, undifferentiated: < 5%
- Depth / extent of invasion: no invasion, cannot determine, into lamina propria, into muscularis mucosa, into submucosa
- Resection margin: cannot assess, positive / negative for invasive carcinoma; if negative, closest tumor to mucosal margin is __ mm, carcinoma in situ absent / present at mucosal margin
- Angiolymphatic invasion: absent, present for large / small vessels, indeterminate
- Recommended if known but not required for accreditation purposes
- HPV status
- Tumor site
- Polyp configuration: pedunculated, sessile, unknown
- Additional findings: none, colitis, other
Features to report - Local excision (transanal disk excision) - applies to all invasive carcinomas
- Mandatory
- Specimen type: intact, fragmented, other
- Tumor size: at least 1 dimension
- Histologic type: squamous cell carcinoma, adenocarcinoma, mucinous adenocarcinoma, small cell carcinoma, undifferentiated carcinoma, Paget disease, other, carcinoma - cannot determine
- Histologic grade: well, moderate or poorly differentiated, undifferentiated, cannot determine or not applicable; for adenocarcinoma, is based on percentage of tumor that forms glands: well: > 95%, moderate: 50 - 95%, poor: 5 - 49%, undifferentiated: < 5%
- Depth / extent of invasion: no invasion, cannot determine, into lamina propria, into muscularis mucosa, into submucosa
- For each resection margin: cannot assess, positive / negative for invasive carcinoma; if negative, closest tumor is __ mm from margin, carcinoma in situ absent / present at margin
- Angiolymphatic invasion: absent, present for large / small vessels, indeterminate
- pTNM and stage
- Recommended if known but not required for accreditation purposes
- HPV status
- Tumor site
- Tumor configuration: polypoid, infiltrative, ulcerating, other
- Perineural invasion: absent, present
- Additional findings: none, Crohn’s disease, condyloma, dysplasia, Paget disease, other
Features to report - Anus resection - applies to all invasive carcinomas
- Mandatory
- Specimen type: abdominoperineal resection, other, not specified
- Tumor site: anterior wall, anal margin, not specified
- Tumor size: at least 1 dimension
- Histologic type: squamous cell carcinoma, adenocarcinoma, mucinous adenocarcinoma, small cell carcinoma, undifferentiated carcinoma, Paget disease, other, carcinoma - cannot determine
- Histologic grade: well, moderate or poorly differentiated, undifferentiated, cannot determine or not applicable; for adenocarcinoma, is based on percentage of tumor that forms glands: well: > 95%, moderate: 50 - 95%, poor: 5 - 49%, undifferentiated: < 5%
- Depth / extent of invasion: no invasion, cannot determine, into lamina propria, into muscularis mucosa, into submucosa, into muscularis propria, into subserosa
- For each resection margin (proximal, distal, radial [soft tissue closest to deepest tumor penetration]): cannot assess, positive / negative for invasive carcinoma; if negative, closest tumor is __ mm from margin, carcinoma in situ absent / present at margin
- Angiolymphatic invasion: absent, present for large / small vessels, indeterminate
- Invasion of other structures
- Nodal involvement (# identified, # involved)
- pTNM and stage
- Optional
- HPV status
- Tumor configuration: polypoid, infiltrative, ulcerating, other
- Perineural invasion: absent, present
- Additional findings: none, Crohn’s disease, condyloma, dysplasia, Paget disease, fistula, active colitis, polyps, other
- Protocol for the examination of specimens from patients with carcinomas of the anus and anal canal (Arch Pathol Lab Med 2000;124:21)
