Anus and perianal area
Miscellaneous
Features to report for tumors

Author: Nat Pernick, M.D. (see Authors page)

Revised: 23 October 2017, last major update April 2005

Copyright: (c) 2002-2017, PathologyOutlines.com, Inc.

PubMed Search: Anus features to report for tumors

Cite this page: Pernick, N. Features to report for tumors. PathologyOutlines.com website. http://pathologyoutlines.com/topic/anusreport.html. Accessed November 18th, 2017.
Definition / general
  • Mandatory / optional are for accreditation purposes by the American College of Surgeons Committee on Cancer
Polypectomy (excisional biopsy) - applies to all invasive carcinomas
  • Mandatory
    • Polyp size: at least 1 dimension
    • Histologic type: squamous cell carcinoma, adenocarcinoma, mucinous adenocarcinoma, small cell carcinoma, undifferentiated carcinoma, other, carcinoma - cannot determine
    • Histologic grade: well, moderate or poorly differentiated, undifferentiated, cannot determine or not applicable; for adenocarcinoma, is based on percentage of tumor that forms glands: well: > 95%, moderate: 50 - 95%, poor: 5 - 49%, undifferentiated: < 5%
    • Depth / extent of invasion: no invasion, cannot determine, into lamina propria, into muscularis mucosa, into submucosa
    • Resection margin: cannot assess, positive / negative for invasive carcinoma; if negative, closest tumor to mucosal margin is __ mm, carcinoma in situ absent / present at mucosal margin
    • Angiolymphatic invasion: absent, present for large / small vessels, indeterminate
  • Recommended if known but not required for accreditation purposes
    • HPV status
    • Tumor site
    • Polyp configuration: pedunculated, sessile, unknown
    • Additional findings: none, colitis, other
Local excision (transanal disk excision) - applies to all invasive carcinomas
  • Mandatory
    • Specimen type: intact, fragmented, other
    • Tumor size: at least 1 dimension
    • Histologic type: squamous cell carcinoma, adenocarcinoma, mucinous adenocarcinoma, small cell carcinoma, undifferentiated carcinoma, Paget disease, other, carcinoma - cannot determine
    • Histologic grade: well, moderate or poorly differentiated, undifferentiated, cannot determine or not applicable; for adenocarcinoma, is based on percentage of tumor that forms glands: well: > 95%, moderate: 50 - 95%, poor: 5 - 49%, undifferentiated: < 5%
    • Depth / extent of invasion: no invasion, cannot determine, into lamina propria, into muscularis mucosa, into submucosa
    • For each resection margin: cannot assess, positive / negative for invasive carcinoma; if negative, closest tumor is __ mm from margin, carcinoma in situ absent / present at margin
    • Angiolymphatic invasion: absent, present for large / small vessels, indeterminate
    • pTNM and stage
  • Recommended if known but not required for accreditation purposes
    • HPV status
    • Tumor site
    • Tumor configuration: polypoid, infiltrative, ulcerating, other
    • Perineural invasion: absent, present
    • Additional findings: none, Crohn’s disease, condyloma, dysplasia, Paget disease, other
Anus resection - applies to all invasive carcinomas
  • Mandatory
    • Specimen type: abdominoperineal resection, other, not specified
    • Tumor site: anterior wall, anal margin, not specified
    • Tumor size: at least 1 dimension
    • Histologic type: squamous cell carcinoma, adenocarcinoma, mucinous adenocarcinoma, small cell carcinoma, undifferentiated carcinoma, Paget disease, other, carcinoma - cannot determine
    • Histologic grade: well, moderate or poorly differentiated, undifferentiated, cannot determine or not applicable; for adenocarcinoma, is based on percentage of tumor that forms glands: well: > 95%, moderate: 50 - 95%, poor: 5 - 49%, undifferentiated: < 5%
    • Depth / extent of invasion: no invasion, cannot determine, into lamina propria, into muscularis mucosa, into submucosa, into muscularis propria, into subserosa
    • For each resection margin (proximal, distal, radial [soft tissue closest to deepest tumor penetration]): cannot assess, positive / negative for invasive carcinoma; if negative, closest tumor is __ mm from margin, carcinoma in situ absent / present at margin
    • Angiolymphatic invasion: absent, present for large / small vessels, indeterminate
    • Invasion of other structures
    • Nodal involvement (# identified, # involved)
    • pTNM and stage
  • Optional
    • HPV status
    • Tumor configuration: polypoid, infiltrative, ulcerating, other
    • Perineural invasion: absent, present
    • Additional findings: none, Crohn’s disease, condyloma, dysplasia, Paget disease, fistula, active colitis, polyps, other