Bone chapter (nontumor and tumor)

See also Bone marrow-nonneoplasticJointsMandible/maxilla, Soft tissue

Authors: Dariusz Borys, M.D., David Lucas, M.D., Sheren Younes, M.D. (see Authors page)

Revised: 27 August 2015, last major update IN PROGRESS

Copyright: (c) 2003-2015, PathologyOutlines.com, Inc.

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Table of contents

General: primary referencesanatomyhistologybone formation & growthbiopsy

Developmental abnormalities: achondrogenesisachondroplastic dwarfismbone islandfibrodysplasia ossificans progressivamalformationsscoliosissyndromesthanatophoric dwarfism

Osteomyelitis: generalactinomycosisamebicbacterialchronic multifocalechinococcusfungalperiostitissyphilitictuberculousxanthogranulomatous

Non-neoplastic or metabolic disease: aseptic bone necrosisblack boneblack cartilagecartilaginous restfracturegiant cystic arachnoid granulationsglomus coccygeumhyperostosis cranii ex vacuohyperparathyroidismhypophosphatasiainfarctmetal toxicitymucopolysaccharidosesnecrosisosteogenesis imperfectaosteopathia striataosteopetrosisosteopoikilosisosteoporosisPaget diseaseradiation necrosisrenal osteodystrophyrickets / osteomalaciaSAPHO syndrome

Fibrous / fibroosseous tumors of bone: cortical irregularities of femurfibrous dysplasiafracture callusliposclerosing myxofibrous tumormetaphyseal fibrous defectmyositis ossificansossifying fibromaosteofibrous dysplasiapost-traumatic

Bone forming tumors (not osteosarcoma): generaladamantinomametastatic calcificationossifying fibromyxoid tumorosteoblastomaosteoid osteomaosteoma

Osteosarcoma: osteosarcoma-generalchemotherapy effectanaplasticepithelioidfibrohistiocytichigh grade surfacelow grade centralosteoblastoma-likePaget disease associatedparostealperiostealsmall celltelangiectaticwell differentiated intramedullary

Cartilage forming tumors (not chondrosarcoma): bizarre parosteal osteochondromatous proliferationschondroblastomachondromachondromyxoid fibromamesenchymomaosteochondroma

Chondrosarcoma: chondrosarcoma-generalconventionalclear celldedifferentiatedmesenchymalmyxoidsecondary

Hematologic neoplasms: lymphoma-generalacute leukemiaanaplastic large cell lymphomaBurkitt lymphomadiffuse large B cell lymphomaHodgkin lymphomalymphoblastic lymphomamastocytosismyeloid sarcomamyelomaplasmacytoma

Vascular tumors: angiosarcomaepithelioid hemangioendotheliomaglomus tumorhemangiomahemangioendotheliomahemangiopericytomalymphangioma

Other tumors of bone: amyloidaneurysmal bone cystbenign fibrous histiocytomabenign notochordal cell tumorsbrown tumor of hyperparathyroidismchest wall hamartomachordomacyst of degenerative joint diseasedesmoplastic fibromadesmoplastic small cell tumorecchordosis physaliphoraepidermoid inclusion cystErdheim-ChesterEwing/PNETfibrosarcomaganglion cyst of bonegiant cell granulomagiant cell tumorimplant related sarcomainfantile myofibromatosisinflammatory myofibroblastic tumorLangerhans cell histiocytosisleiomyosarcomalipomaliposarcomamalignant fibrous histiocytomamalignant peripheral nerve sheath tumormassive osteolysismeloreostosismetastases to bonemyofibrosarcomamyxomaneurofibromaosteitis fibrosa cysticaosteochondromyxomaphosphaturic mesenchymal tumorpost-radiation sarcomarhabdomyosarcomaschwannomasinus histiocytosis with massive lymphadenopathysolitary bone cystsolitary fibrous tumorsubungual exostosissubungual keratoacanthomaxanthoma

Miscellaneous: features to reportgrossingstaging-not myelomastaging-myeloma



Index (Alphabetical table of contents)

A-E: achondrogenesisachondroplastic dwarfismactinomycosisacute leukemiaadamantinomaamebic osteomyelitis amyloidanaplastic large cell lymphomaanaplastic osteosarcomaanatomyaneurysmal bone cystangiosarcomaaseptic bone necrosisbacterial osteomyelitis benign fibrous histiocytomabenign notochordal cell tumorsbiopsybizarre parosteal osteochondromatous proliferationsblack boneblack cartilagebone formation & growthbone forming tumors-generalbone islandbrown tumor of hyperparathyroidismBurkitt lymphomacartilaginous restchemotherapy effectchest wall hamartomachondroblastomachondromachondromyxoid fibromachondrosarcoma-generalchordomachronic multifocal osteomyelitis clear cell chondrosarcomaconventional chondrosarcomacortical irregularities of femurcyst of degenerative joint diseasededifferentiated chondrosarcomadesmoplastic fibromadesmoplastic small cell tumordiffuse large B cell lymphomaecchordosis physaliphoraechinococcus osteomyelitis epidermoid inclusion cystepithelioid hemangioendotheliomaepithelioid osteosarcomaErdheim-ChesterEwing/PNET

F-N: features to reportfibrodysplasia ossificans progressivafibrohistiocytic osteosarcomafibrosarcomafibrous dysplasiafracturefracture callusfungal osteomyelitis ganglion cyst of bonegiant cell granulomagiant cell tumorgiant cystic arachnoid granulationsglomus coccygeumglomus tumorgrossinghemangiomahemangioendotheliomahemangiopericytomahigh grade surface osteosarcomahistologyHodgkin lymphomahyperostosis cranii ex vacuohyperparathyroidismhypophosphatasiaimplant related sarcomainfantile myofibromatosisinfarctinflammatory myofibroblastic tumorLangerhans cell histiocytosisleiomyosarcomalipomaliposarcomaliposclerosing myxofibrous tumorlow grade central osteosarcomalymphangiomalymphoblastic lymphomalymphoma-generalmalformationsmalignant fibrous histiocytomamalignant peripheral nerve sheath tumormassive osteolysismastocytosismeloreostosismesenchymal chondrosarcomamesenchymomametal toxicitymetaphyseal fibrous defectmetastases to bonemetastatic calcificationmucopolysaccharidosesmyeloid sarcomamyelomamyofibrosarcomamyositis ossificansmyxoid chondrosarcomamyxomanecrosisneurofibroma

O-Z: ossifying fibromaossifying fibromyxoid tumorosteitis fibrosa cysticaosteoblastomaosteoblastoma-like osteosarcomaosteochondromaosteochondromyxomaosteofibrous dysplasiaosteogenesis imperfectaosteoid osteomaosteomaosteomyelitis-generalosteopathia striataosteopetrosisosteopoikilosisosteoporosisosteosarcoma-generalPaget diseasePaget disease associated osteosarcomaparosteal osteosarcomaperiosteal osteosarcomaperiostitisphosphaturic mesenchymal tumorplasmacytomapost-radiation sarcomapost-traumaticprimary referencesradiation necrosisrenal osteodystrophyrhabdomyosarcomarickets / osteomalaciaSAPHO syndromeschwannomascoliosissecondary chondrosarcomasinus histiocytosis with massive lymphadenopathysmall cell osteosarcomasolitary bone cystsolitary fibrous tumorstaging-myelomastaging-not myelomasubungual exostosissubungual keratoacanthomasyndromessyphilitic osteomyelitis telangiectatic osteosarcomathanatophoric dwarfismtuberculous osteomyelitis well differentiated intramedullary osteosarcomaxanthogranulomatous osteomyelitis xanthoma


Primary references:
top

AJCC Cancer Staging Manual (7th ed)
Websites: PathoPic, www.BoneTumor.org



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